A high proportion of malignant cells in the NHPrE1/AR grafts showed nuclear immunoreactivity for the cell proliferation marker Ki67 (Figures ?(Numbers5K5K and ?and5L),5L), but only a few positive nuclei were seen in the stratified luminal epithelial cells from NHPrE1/EV grafts (Numbers ?(Numbers5We5I and ?and5J)

A high proportion of malignant cells in the NHPrE1/AR grafts showed nuclear immunoreactivity for the cell proliferation marker Ki67 (Figures ?(Numbers5K5K and ?and5L),5L), but only…