Together, these relationships push the iron-bound CN to look at a unique bent conformation (using the FeCCCN position of ~137) and placement its nitrogen atom following towards the C2 atom from the Trp within an oxyanion opening, produced up from the ammonium and indoleamine sets of the Trp as well as the peptide amide band of A264

Together, these relationships push the iron-bound CN to look at a unique bent conformation (using the FeCCCN position of ~137) and placement its nitrogen atom…

Here we explored the mechanism of Fatostatin’s antitumor activity and determined that in addition to inhibiting lipid metabolism, Fatostatin also inhibits tubulin polymerization, which perturbs mitotic spindle assembly and leads to mitotic catastrophe

Here we explored the mechanism of Fatostatin’s antitumor activity and determined that in addition to inhibiting lipid metabolism, Fatostatin also inhibits tubulin polymerization, which perturbs…